What's New List Serve Post Display

What's New List Serve Post Display

Below is the List Serve Post you selected to display.
newsrel -- Components of particle pollution may contribute to heart disease

Posted: 11 Oct 2013 11:07:25
Please consider the following news release from the California
Air Resources Board:



News Release 13-63

October 11, 2013

Melanie Turner
(916) 322-2990

Components of particle pollution may contribute to heart disease

UC Irvine study uses novel approach to better understand toxicity
of particles

Sacramento — Specific components of particles may be linked to
the progression of heart disease, the leading cause of death in
the U.S., according to a study released today by the California
Air Resources Board. 

Funded by the Air Resources Board and led by Dr. Michael T.
Kleinman of the University of California Irvine, the study used a
novel approach to look at health impacts associated with exposure
to particles, 0.18 microns in diameter or smaller. A human hair
is about 60 microns in diameter, or at least 300 times wider than
the diameter of particles examined in the study. 

The particles examined in this study are a subset of particle
pollution known as PM10 and PM2.5, particulate matter that is
equal to or less than 10 and 2.5 microns in diameter,

Numerous scientific studies have linked exposure to PM2.5, which
can be deeply inhaled into the airways and lungs, to a variety of
problems, including premature death, especially in people with
pre-existing heart disease.

The particles used in this study, which come primarily from
internal-combustion exhaust and from chemical reactions in the
air, may pose a great health risk, yet relatively little is known
about the emissions, exposures or health effects of these
ultrafine particles. In the UC Irvine study, scientists used a
heating method to remove most of the organic chemical compounds
from particles, leaving behind most inorganics to examine the
health effects of these particles’ component parts. Laboratory
mice exposed to either fully intact particles or just the organic
components of the particles had more rapid development of
atherosclerotic plaques, compared to mice exposed to particles
without the organics. The intact particles also had other
negative effects on heart health. Atherosclerosis is hardening of
the arteries, a factor contributing to heart attacks.

Dr. Kleinman, professor and co-director of the Air Pollution
Health Effects Laboratory from the Division of Occupational and
Environmental Health, Department of Medicine, UC Irvine, was the
principal investigator on the study, titled, “Cardiopulmonary
Health Effects: Toxicity of Semi-Volatile and Non-Volatile
Components of PM.”

The study provides information that is significant to help the
Air Resources Board expand its understanding of the role of
different components of exhaust emissions so that the ARB can
better target control policies. Reducing particulate matter air
pollution is one of California’s highest public health

ARB’s Advanced Clean Cars and diesel control programs are
reducing emissions of this harmful pollution. Projected emission
reduction benefits associated with full implementation of ARB’s
Diesel Risk Reduction Plan are reductions in diesel particulate
matter emissions and associated cancer risk of 85 percent by
2020, compared to 2000 levels. 

Dr. Kleinman presented his findings at a seminar on October 9,
2013, at the Cal/EPA Headquarters Building, 1001 I St.,
Sacramento. Link to the presentation and the report here:

ARB What's New