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arbcombo -- Research Seminar: Intrinsic Ability of Particles to Generate Reactive Oxygen Species and the Effect of Physiologically Relevant Solutes

Posted: 03 Aug 2016 16:11:24
Suzanne Paulson, PhD, UC Los Angeles, 
Cort Anastasio, PhD, UC Davis, and 
Alam Hasson, PhD, California State University, Fresno. 

Thursday, September 1, 2016 1:30 p.m., PDT (WEBCAST)
Sierra Hearing Room, 2nd Floor, Cal/EPA Building
1001 I Street, Sacramento, California

Oxidative stress mediated by reactive oxygen species (ROS) is a
leading hypothesis for the mechanism by which particulate
pollution contributes to a range of illnesses, including asthma
and cardiovascular mortality. The goal of this study was to
understand the components in particles responsible for ROS
formation under physiological conditions. The investigators
conducted a field campaigns in the South Coast Air Basin, aimed
at capturing photochemical smog; and in Fresno, which has
significant contributions from biomass burning. Samples were
extracted in simulated lung fluid, and analyzed for their ability
to generate ROS such as hydrogen peroxide (H₂O₂) and
hydroxyl radical (.OH) and to consume dithiothreitol (DTT) The
contributions of transition metals and quinones to ROS formation
was also investigated. For more go to the announcement at:
http://www.arb.ca.gov/research/seminars/paulson4/paulson4.htm

Main menu:
   http://www.arb.ca.gov/research/seminars/seminars.htm

Webcast:  http://www.calepa.ca.gov/broadcast/?bdo=1

Please send your-e-mail for the Q&A participation
to:   sierrarm@calepa.ca.gov

For more information please contact:
   Dongmin Luo, Ph.D. at (916) 324-8496 or
Dongmin.Luo@arb.ca.gov

For more information on the Seminar Series please contact:
   Peter Mathews at (916) 323-8711 or Peter.Mathews@arb.ca.gov

To receive notices for upcoming Seminars please go to: 
   http://www.arb.ca.gov/listserv/listserv.php
   and sign up for the seminars list serve.


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